This book uncovers the original influences that shaped the creation and the various interpretations of addiction as a disease, and of addiction to opiates in particular. It delves into the treatments, regimes, and prejudices that surrounded the condition, a newly emerging pathological entity and a form of 'moral insanity' during the nineteenth century. Letters, diaries and newspapers are drawn upon to detail personal struggles with addiction and the trials of those who cared and despaired.