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Sperm Nuclear Maturation : A Basic & Clinical Approach, Paperback / softback Book

Sperm Nuclear Maturation : A Basic & Clinical Approach Paperback / softback


In somatic cells, DNA is normally wrapped around the histones octamer to forms nucleosomes that eventually give rise to a solenoid DNA structure.

Unlike somatic cells, in mammalian sperm, the development of spermatids into mature spermatozoa is accomplished by a series of structural and chemical modifications including a gradual replacement of lysine-rich histones by transition proteins and then by protamines which bind more tightly to DNA than histones, which results in compaction of chromatin in the sperm nucleus, a process which is termed 'sperm chromatin condensation'.

This book examines the several techniques that have been devised in order to study chromatin and DNA defects in human spermatozoa.


  • Format: Paperback / softback
  • Pages: 129 pages
  • Publisher: Nova Science Publishers Inc
  • Publication Date:
  • Category: DNA & Genome
  • ISBN: 9781616681944



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