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Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy, Hardback Book

Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy Hardback


Since the completion of the first edition of this book, major developments have occurred in the pharmaceutical industry that have shaped the field of near-infrared (NIR) spectroscopy.

A new initiative from the U.S. Food and Drug Administration (FDA) to modernize regulations of pharmaceutical manufacturing and drug quality has helped position NIR spectroscopy as an effective tool for pharmaceutical testing.

Pharmaceutical and Medical Applications of Near-Infrared Spectroscopy: Second Edition reflects these developments and brings readers an up-to-date summary of how this technique is being applied to pharmaceutical manufacturing. Topics include:The origins and principles of NIR spectroscopy, including early instrumentation, spectroscopic theory, and light-particle interactionThe physics of each instrument type, the strengths and weaknesses of each, and the manufacturers that produce themThe possible advantages of using NIR methods for monitoring or controlling blending, as well as practical concerns for mixing processesNIR spectroscopy as applied to traditional granulation, drug layering, and film coating of beads or granulesPharmaceutical assays, including qualitative analysis, quantitative analysis, determination of actives in tablets and capsules, and considerations for intact dosage form analysisSteps involved in the validation and acceptance of an NIR spectroscopy method, including quality assurance, qualification and verification of instruments, and the International Conference on Harmonization (ICH) guidelinesMedical applications, including those related to blood glucose measurements, tissue and major organ analysis, fetal analysis, and cancer researchProviding comprehensive coverage of NIR spectroscopy, from theory, mathematics, application, and mechanics of NIR analysis, the book supplies ample references to facilitate further rese


  • Format: Hardback
  • Pages: 172 pages
  • Publisher: Taylor & Francis Inc
  • Publication Date:
  • Category: Analytical chemistry
  • ISBN: 9781420084146

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