Comprehensive Analysis of Parasite Biology : From Metabolism to Drug Discovery Hardback
by Ewelina Guca
Edited by Sylke Muller, Rachel Cerdan, Ovidiu Radulescu
Part of the Drug Discovery in Infectious Diseases series
Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa.
The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling.
Furthermore, state-of the art "omics" technologies are described and currently studied enzymatic drug targets are discussed.
Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification.
In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.
- Format: Hardback
- Pages: 576 pages
- Publisher: Wiley-VCH Verlag GmbH
- Publication Date: 31/08/2016
- Category: Pharmacology
- ISBN: 9783527339044