Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 2: Microdialysis And Sensing Of Neural Tissues Hardback
Edited by George S. Wilson, Adrian C. Michael
Volume 1 of this series focused mainly on small molecules which are intrinsically electroactive.
Volume 2 continues to provide current approaches to real time measurements of essential species in the central nervous system.
It describes microdialysis, a sampling technique, which facilitates the removal of small volumes of solution containing the analyte(s) of interest which can be subsequently separated by chromatography and analyzed by a range of techniques.
These include electrochemistry, UV-Vis spectroscopy, fluorescence and mass spectroscopy.
This approach affords the opportunity to measure a range of targets in real-time thus providing access to pharmacokinetic/pharmacodynamics measurements affording the possibility of measuring the disappearance of a drug after administration and the subsequent appearance of metabolites.
Microdialysis further affords the ability to sample peptides and proteins of neurobiological interest.Consistent with the goals of Volume 1, Volume 2 seeks to provide for scientists in the field of neurobiology a base of bioanalytical techniques that may not be familiar to them.
Specific examples are provided and the fundamental basis of the technique is also covered.
- Format: Hardback
- Pages: 424 pages
- Publisher: World Scientific Publishing Co Pte Ltd
- Publication Date: 23/08/2017
- Category: Neurosciences
- ISBN: 9789813220539