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Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 2: Microdialysis And Sensing Of Neural Tissues, Hardback Book

Compendium Of In Vivo Monitoring In Real-time Molecular Neuroscience - Volume 2: Microdialysis And Sensing Of Neural Tissues Hardback

Edited by George S. Wilson, Adrian C. Michael

Description

Volume 1 of this series focused mainly on small molecules which are intrinsically electroactive.

Volume 2 continues to provide current approaches to real time measurements of essential species in the central nervous system.

It describes microdialysis, a sampling technique, which facilitates the removal of small volumes of solution containing the analyte(s) of interest which can be subsequently separated by chromatography and analyzed by a range of techniques.

These include electrochemistry, UV-Vis spectroscopy, fluorescence and mass spectroscopy.

This approach affords the opportunity to measure a range of targets in real-time thus providing access to pharmacokinetic/pharmacodynamics measurements affording the possibility of measuring the disappearance of a drug after administration and the subsequent appearance of metabolites.

Microdialysis further affords the ability to sample peptides and proteins of neurobiological interest.Consistent with the goals of Volume 1, Volume 2 seeks to provide for scientists in the field of neurobiology a base of bioanalytical techniques that may not be familiar to them.

Specific examples are provided and the fundamental basis of the technique is also covered.

Information

  • Format: Hardback
  • Pages: 424 pages
  • Publisher: World Scientific Publishing Co Pte Ltd
  • Publication Date:
  • Category: Neurosciences
  • ISBN: 9789813220539

£148.00

£127.55

 
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