Greener than conventional methods, C-H activation methods have flourished during the last decade and become especially attractive to organic chemists.
Edited by a practioner in this rapidly developing field, C-H Bond Activation in Organic Synthesis provides an overview of this exciting playground of chemistry.
The book summarizes the state of the art in C-H activation for functionalization, enabling you to carry out reactions in the most environmentally friendly fashion with the least contamination of by-products.
The most popular C-H activation reactions are catalyzed by transition metals.
This book dedicates a chapter to each of the following catalysts: palladium, rhodium, nickel, iron, copper, and cobalt.
In addition, it covers radical-mediated C-H activation, fluorination via C-H activation, and C-H activation of heterocycles.
Using a pedagogically practical approach, each chapter is divided by the transition metal catalyst, not a specific transformation.
This gives you an up-to-date review of the most important topics of C-H activation. The area of C-H activation has experienced a flurry of activity over the past two decades, so the time is right for a resource that summarizes these powerful tools with which you can design and construct heteroaromatic molecules.
Thus, direct C-H functionalization methods are expected to continue to greatly contribute to the mission of green chemistry: low-energy, waste-free, and atom-economic transformations for the synthesis of organic materials and biologically active molecules in the twenty-first century.
Using this book, you can carry out environmentally friendly reactions that enable the conversion of cheap and abundant alkanes into valuable functionalized organic compounds.