C-H Bond Activation in Organic Synthesis, Hardback Book

C-H Bond Activation in Organic Synthesis Hardback

Edited by Jie Jack (Revolution Medicines, California, USA) Li


Greener than conventional methods, C-H activation methods have flourished during the last decade and become especially attractive to organic chemists.

Edited by a practioner in this rapidly developing field, C-H Bond Activation in Organic Synthesis provides an overview of this exciting playground of chemistry.

The book summarizes the state of the art in C-H activation for functionalization, enabling you to carry out reactions in the most environmentally friendly fashion with the least contamination of by-products.

The most popular C-H activation reactions are catalyzed by transition metals.

This book dedicates a chapter to each of the following catalysts: palladium, rhodium, nickel, iron, copper, and cobalt.

In addition, it covers radical-mediated C-H activation, fluorination via C-H activation, and C-H activation of heterocycles.

Using a pedagogically practical approach, each chapter is divided by the transition metal catalyst, not a specific transformation.

This gives you an up-to-date review of the most important topics of C-H activation. The area of C-H activation has experienced a flurry of activity over the past two decades, so the time is right for a resource that summarizes these powerful tools with which you can design and construct heteroaromatic molecules.

Thus, direct C-H functionalization methods are expected to continue to greatly contribute to the mission of green chemistry: low-energy, waste-free, and atom-economic transformations for the synthesis of organic materials and biologically active molecules in the twenty-first century.

Using this book, you can carry out environmentally friendly reactions that enable the conversion of cheap and abundant alkanes into valuable functionalized organic compounds.


  • Format: Hardback
  • Pages: 327 pages, 49 Tables, black and white; 475 Illustrations, black and white
  • Publisher: Apple Academic Press Inc.
  • Publication Date:
  • Category: Organic chemistry
  • ISBN: 9781482233100



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