When fun-loving, eighteen-stone Eileen Gillmoss announces that she's expecting a baby, her husband Bill thinks it's another one of her jokes.
After all, it's twelve years since Edna, their youngest, was born.
But when it sinks in that a baby really is on the way, Bill is over the moon and decides that the family should move out of their two-up, two-down house in Liverpool to one with more spacious accommodation.
Eileen digs her heels in at first, reluctant to leave the house she loves and friends and neighbours so dear.
But a scare early in Eileen's pregnancy strengthens Bill's resolve to provide a more comfortable home for his wife.
Before Eileen knows what's hit her, she's installed in a smart home with posh new neighbours.
Then tragedy strikes and Eileen must come to terms with a loss far greater than leaving behind her beloved neighbourhood.
She tries to put on a brave face, but she can't fool the people who love her, who miss the smile on that round, chubby face and the laughter ringing through her house.
They vow to make amends and fate steps in to lend a helping hand...