Cancer stem cells (CSCs) are cancer cells that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample.
CSCs are therefore tumorigenic (tumour-forming), perhaps in contrast to other non-tumorigenic cancer cells.
CSCs may generate tumours through the stem cell processes of self-renewal and differentiation into multiple cell types.
This book presents new research on cancer stem cells including mesenchymal stem cells and their role in tumour progression; Wnt signalling in colon cancer stem cells; genetic and epigenetic alterations that drive leukaemic stem cell self-renewal and others.
- Format: Hardback
- Pages: 191 pages, tables, diagrams, illus.
- Publisher: Nova Science Publishers Inc
- Publication Date: 19/03/2011
- Category: Cellular physiology
- ISBN: 9781616689711