TDP-43 and Neurodegeneration : From Bench to Bedside Paperback / softback
Edited by Vijay (Assistant Professor, Amity Institute of Neuropsychology and Neurosciences, Amity Unive Kumar, Manoj Kumar (Department of Psychiatry, Icahn School of Medicine at Mount Sina, New York, NY Jaiswal
Paperback / softback
Description
Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features.
TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies.
The book summarizes TDP-43's structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics.
It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases.
This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders.
Information
-
Out of stock
- Format:Paperback / softback
- Pages:270 pages
- Publisher:Elsevier Science Publishing Co Inc
- Publication Date:27/10/2021
- Category:
- ISBN:9780128200667
Information
-
Out of stock
- Format:Paperback / softback
- Pages:270 pages
- Publisher:Elsevier Science Publishing Co Inc
- Publication Date:27/10/2021
- Category:
- ISBN:9780128200667