Regulation of Vitamin A Homeostasis by the Stellate Cell (Vitamin A-Storing Cell) System Paperback / softback
by Haruki Senoo, Kiwamu Yoshikawa, Yoshihiro Mezaki, Mayako Morii, Mutsunori Fujiwara
Paperback / softback
Description
Vitamin A-storing cells in the liver exist in the space between parenchymal cells and liver sinusoidal endothelial cells of the hepatic lobule, and store 50-80% of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm.
In physiological conditions, these cells play pivotal roles in the regulation of vitamin A homeostasis.
In pathological conditions such as hepatic fibrosis or liver cirrhosis, hepatic stellate cells lose vitamin A, and synthesise a large amount of extracellular matrix components including collagen, proteoglycan, glycosaminoglycan, and adhesive glycoproteins.
Morphology of these cells also changes from the star-shaped stellate cells to that of fibroblasts or myofibroblasts.
This book discusses and presents research on vitamin A-storing cells.
Information
-
Out of stock
- Format:Paperback / softback
- Pages:55 pages
- Publisher:Nova Science Publishers Inc
- Publication Date:16/02/2011
- Category:
- ISBN:9781617613135
Information
-
Out of stock
- Format:Paperback / softback
- Pages:55 pages
- Publisher:Nova Science Publishers Inc
- Publication Date:16/02/2011
- Category:
- ISBN:9781617613135