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The Development of the Perineum in the Human : A Comprehensive Histological Study with a Special Reference to the Role of the Stromal Components, Paperback / softback Book

The Development of the Perineum in the Human : A Comprehensive Histological Study with a Special Reference to the Role of the Stromal Components Paperback / softback

Part of the Advances in Anatomy, Embryology and Cell Biology series

Paperback / softback

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References...126 Subject Index...133 1 Introduction The developmental steps which lead to the formation of the human perineum seem firmly established (Arey 1965; Hamilton and Mossman1972; Moore and Persaud 1998; Wartenberg 1993; Sadler 1995; Larsen 1997).

They form the base for the evaluation of the pathogenesis of a great variety of complicated and often serious malformations which occur in this region.

This concept has, however, been challenged by the results of an investigation into the n- mal and abnormal development of the anorectum in pig (van der Putte and Neeteson 1983, 1984; van der Putte 1986).

Observations revealed that at least in pig, a major element in current ideas about the early development of the perineum, namely the process by which the original simple cloaca is sub- vided into a urogenital and anal part is incorrect, while additional obser- tions strongly suggested that the same may be true for ideas about female and male sexual transformation.

A preliminary investigation in human - bryos gave similar indications (van der Putte 1986). The data supported e- lier critical findings (Politzer 1931, 1932; Wijnen 1964; Ludwig 1965) which have apparently been ignored, possibly because they seemed to hinder the understanding of the pathogenesis of congenital malformations such as - perforate anus and hypospadias.

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  • Format:Paperback / softback
  • Pages:136 pages, 46 Illustrations, black and white; XII, 136 p. 46 illus.
  • Publisher:Springer-Verlag Berlin and Heidelberg GmbH & Co. K
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  • ISBN:9783540210399

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Information

  • Item not Available

  • Format:Paperback / softback
  • Pages:136 pages, 46 Illustrations, black and white; XII, 136 p. 46 illus.
  • Publisher:Springer-Verlag Berlin and Heidelberg GmbH & Co. K
  • Publication Date:
  • Category:
  • ISBN:9783540210399