Protein Interaction Networks : Computational Analysis Hardback
by Aidong (State University of New York, Buffalo) Zhang
Hardback
Description
The analysis of protein-protein interactions is fundamental to the understanding of cellular organization, processes, and functions.
Proteins seldom act as single isolated species; rather, proteins involved in the same cellular processes often interact with each other.
Functions of uncharacterized proteins can be predicted through comparison with the interactions of similar known proteins.
Recent large-scale investigations of protein-protein interactions using such techniques as two-hybrid systems, mass spectrometry, and protein microarrays have enriched the available protein interaction data and facilitated the construction of integrated protein-protein interaction networks.
The resulting large volume of protein-protein interaction data has posed a challenge to experimental investigation.
This book provides a comprehensive understanding of the computational methods available for the analysis of protein-protein interaction networks.
It offers an in-depth survey of a range of approaches, including statistical, topological, data-mining, and ontology-based methods.
The author discusses the fundamental principles underlying each of these approaches and their respective benefits and drawbacks, and she offers suggestions for future research.
Information
-
Out of stock
- Format:Hardback
- Pages:292 pages, 30 Tables, unspecified; 11 Plates, color; 79 Line drawings, unspecified
- Publisher:Cambridge University Press
- Publication Date:06/04/2009
- Category:
- ISBN:9780521888950
Information
-
Out of stock
- Format:Hardback
- Pages:292 pages, 30 Tables, unspecified; 11 Plates, color; 79 Line drawings, unspecified
- Publisher:Cambridge University Press
- Publication Date:06/04/2009
- Category:
- ISBN:9780521888950
