Formulation of Film Coated Tablets of Norfloxacin and Tinidazole Paperback / softback
by Anilkumar Shinde, Harinath More
Paperback / softback
Description
The aim of the present study was development and optimization of an efficacious, pharmaco-economical, palatable and marketable film coated tablet formulation of Norfloxacin-Tinidazole.
Bitter taste of both drugs reduces the patient compliance & hence marketability.
However it has been shown that film coating technology economical & useful in masking the taste.
The core tablets with maximum hardness & minimum disintegration time were selected for film coating. (F-1 & F-07) The optimized formulation F-07 showed hardness, friability, disintegration time and drug release in range 9 kg/cm2, 0.17±0.02%, 27.40±2.1 sec. & 100% release in 30 min. respectively. For all tablet formulation drug release at the end of 30 min was found in the range of 52.78±0.09 to 100.07±0.5 % and from the obtained results, F-07 was selected as an optimized formulation for designing palatable tablet.
Therefore it can be concluded that the present work discusses in depth the development and optimization of an efficacious, pharmaco-economical, palatable and marketable tablet formulation of Norfloxacin and Tinidazole.
Information
-
Out of stock
- Format:Paperback / softback
- Pages:96 pages
- Publisher:LAP Lambert Academic Publishing
- Publication Date:13/12/2018
- Category:
- ISBN:9786139977369
Information
-
Out of stock
- Format:Paperback / softback
- Pages:96 pages
- Publisher:LAP Lambert Academic Publishing
- Publication Date:13/12/2018
- Category:
- ISBN:9786139977369
