![Nonsense Mutation Correction in Human Diseases : An Approach for Targeted Medicine, Paperback / softback Book Nonsense Mutation Correction in Human Diseases : An Approach for Targeted Medicine, Paperback / softback Book](http://hive.dmmserver.com/media/640/97801280/9780128044681.jpg)
Nonsense Mutation Correction in Human Diseases : An Approach for Targeted Medicine Paperback / softback
by Fabrice (Institut Pasteur de Lille, 1 rue Calmette Professor, Lille, France) Lejeune, Hana (Mecanismes de la Tumorigenese et Therapies Ciblees - M3T - UMR, Universite de Lill Benhabiles, Jieshuang (Centre National de la Recherche Scientifique (CNRS) - UMR, Paris, France) Jia
Paperback / softback
Description
Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD). It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinical trials to further support this basis.
In addition, the book shows how it may be possible to combine several of these strategies to ultimately improve the efficiency of correction, also suggesting the future goals and objectives to improve treatment modalities in this evolving sphere of personalized medicine.
Information
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Available to Order - This title is available to order, with delivery expected within 2 weeks
- Format:Paperback / softback
- Pages:190 pages
- Publisher:Elsevier Science Publishing Co Inc
- Publication Date:21/04/2016
- Category:
- ISBN:9780128044681
Information
-
Available to Order - This title is available to order, with delivery expected within 2 weeks
- Format:Paperback / softback
- Pages:190 pages
- Publisher:Elsevier Science Publishing Co Inc
- Publication Date:21/04/2016
- Category:
- ISBN:9780128044681