Please note: In order to keep Hive up to date and provide users with the best features, we are no longer able to fully support Internet Explorer. The site is still available to you, however some sections of the site may appear broken. We would encourage you to move to a more modern browser like Firefox, Edge or Chrome in order to experience the site fully.

Supporting your high street Find out how »
DNA Topoisomerases and Cancer, PDF eBook

DNA Topoisomerases and Cancer PDF

Edited by Yves Pommier

Part of the Cancer Drug Discovery and Development series

PDF

Download - Immediately Available
Please note: eBooks can only be purchased with a UK issued credit card and all our eBooks (ePub and PDF) are DRM protected.

Description

DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It will describe how topoisomerase dysfunctions can damage the genome and increase the risk of cancers, and the involvement of topoisomerases in programmed cell death. The book will also present the various topoisomerase inhibitors in clinical use and development and their molecular and cellular mechanisms of action.

Information

Save 14%

£179.50

£152.58

Download - Immediately Available
Add to Basket
Sign in to add to wishlist
 
Delivered to your inbox

to transfer to your device

eBook Help

Is this the right eBook for
my device? How do I download
this eBook? See help and FAQs pages

Information

Also in the Cancer Drug Discovery and Development series  |  View all

Targeting the DNA Damage Response for...

£179.99

£169.35

Add to Basket

Innovations for Next-Generation...

£129.99

£123.05

Add to Basket

Developments in T Cell Based Cancer...

£129.99

£123.05

Add to Basket

PI3K-mTOR in Cancer and Cancer Therapy

£129.99

£123.05

Add to Basket