Inhibitors of Protein–Protein Interactions : Small Molecules, Peptides and Macrocycles Hardback
Edited by Ali (University of Southhampton, United Kingdom) Tavassoli
Part of the Chemical Biology series
Hardback
Description
Protein–protein interactions (PPI) are at the heart of the majority of cellular processes, and are frequently dysregulated or usurped in disease.
Given this central role, the inhibition of PPIs has been of significant interest as a means of treating a wide variety of diseases.
However, there are inherent challenges in developing molecules capable of disrupting the relatively featureless and large interfacial areas involved.
Despite this, there have been a number of successes in this field in recent years using both traditional drug discovery approaches and innovative, interdisciplinary strategies using novel chemical scaffolds.
This book comprehensively covers the various aspects of PPI inhibition, encompassing small molecules, peptidomimetics, cyclic peptides, stapled peptides and macrocycles.
Illustrated throughout with successful case studies, this book provides a holistic, cutting-edge view of the subject area and is ideal for chemical biologists and medicinal chemists interested in developing PPI inhibitors.
Information
-
Available to Order - This title is available to order, with delivery expected within 2 weeks
- Format:Hardback
- Pages:356 pages
- Publisher:Royal Society of Chemistry
- Publication Date:07/12/2020
- Category:
- ISBN:9781788015691
Information
-
Available to Order - This title is available to order, with delivery expected within 2 weeks
- Format:Hardback
- Pages:356 pages
- Publisher:Royal Society of Chemistry
- Publication Date:07/12/2020
- Category:
- ISBN:9781788015691
