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The Serotonin Receptors : From Molecular Pharmacology to Human Therapeutics, Paperback / softback Book

The Serotonin Receptors : From Molecular Pharmacology to Human Therapeutics Paperback / softback

Edited by Bryan L. Roth

Part of the The Receptors series

Paperback / softback

Description

A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery.

The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted.

They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice.

Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.

Information

  • Format:Paperback / softback
  • Pages:618 pages, 5 Illustrations, color; 77 Illustrations, black and white; XVIII, 618 p. 82 illus., 5 ill
  • Publisher:Humana Press Inc.
  • Publication Date:
  • Category:
  • ISBN:9781617376474
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Information

  • Format:Paperback / softback
  • Pages:618 pages, 5 Illustrations, color; 77 Illustrations, black and white; XVIII, 618 p. 82 illus., 5 ill
  • Publisher:Humana Press Inc.
  • Publication Date:
  • Category:
  • ISBN:9781617376474

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