Matrix Metalloproteases : Methods and Protocols Paperback / softback
Edited by Charles A. Galea
Part of the Methods in Molecular Biology series
Paperback / softback
Description
Since the identification of the first matrix metalloprotease (insterstitial collagenase or MMP-1) more than 20 closely related and evolutionarily conserved vertebrate MMPs have been discovered.
Chapters in this volume detail methods and protocols on recent advances in the expression and purification of MMPs, biophysical methods such as X-ray crystallography, NMR spectroscopy and small angle X-ray scattering, computational and experimental methods for determining MMP specificity, methods for detecting MMP activity in vitro and in vivo, and methods for the development and characterization of MMP-based inhibitors as potential therapeutics for the treatment of various diseases.
Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Matrix Metalloproteases: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Information
-
Out of stock
- Format:Paperback / softback
- Pages:314 pages, 34 Illustrations, color; 22 Illustrations, black and white; XI, 314 p. 56 illus., 34 illu
- Publisher:Humana Press Inc.
- Publication Date:07/08/2018
- Category:
- ISBN:9781493983216
Information
-
Out of stock
- Format:Paperback / softback
- Pages:314 pages, 34 Illustrations, color; 22 Illustrations, black and white; XI, 314 p. 56 illus., 34 illu
- Publisher:Humana Press Inc.
- Publication Date:07/08/2018
- Category:
- ISBN:9781493983216
