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Immunoinformatics : Predicting Immunogenicity in Silico, Hardback Book

Immunoinformatics : Predicting Immunogenicity in Silico Hardback

Edited by Darren R. Flower

Part of the Methods in Molecular Biology series

Hardback

Description

Immunoinformatics: Predicting Immunogenicity In Silico is a primer for researchers interested in this emerging and exciting technology and provides examples in the major areas within the field of immunoinformatics.

This volume both engages the reader and provides a sound foundation for the use of immunoinformatics techniques in immunology and vaccinology. The volume is conveniently divided into four sections.

The first section, Databases, details various immunoinformatic databases, including IMGT/HLA, IPD, and SYEPEITHI.

In the second section, Defining HLA Supertypes, authors discuss supertypes of GRID/CPCA and hierarchical clustering methods, Hla-Ad supertypes, MHC supertypes, and Class I Hla Alleles.

The third section, Predicting Peptide-MCH Binding, includes discussions of MCH binders, T-Cell epitopes, Class I and II Mouse Major Histocompatibility, and HLA-peptide binding.

Within the fourth section, Predicting Other Properties of Immune Systems, investigators outline TAP binding, B-cell epitopes, MHC similarities, and predicting virulence factors of immunological interest. Immunoinformatics: Predicting Immunogenicity In Silico merges skill sets of the lab-based and the computer-based science professional into one easy-to-use, insightful volume.

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