Developmental Toxicology Hardback
by Deborah K. Hansen, Barbara D. Abbott
Part of the Target Organ Toxicology Series series
Hardback
Description
Highlighting latest advances in genetics and biochemistry, the completely revised Third Edition reviews the field from basic science, clinical, epidemiological, and regulatory perspectives.
Contributions from top opinion leaders in the field bring together developments in molecular embryology and cell biology as they apply to problems in developmental toxicology.
It covers testing of pharmaceutical and environmental agents and interpretation of developmental toxicology data, highlighting mathematical and statistical techniques, as well as the effects of toxic exposure on the functional development of various organs. The relationship between maternal and developmental toxicology is examined, in addition to current techniques for studying chemical disposition, metabolism, and placental transfer.
Close attention is given to the regulatory aspects of testing and risk assessment.
Pre- and postconceptional clinical care and genetic factors in clinical developmental toxicology are also discussed. Key topics include: the roles of apoptosis and signal transduction pathways in normal and abnormal developmentthe role of epigenetic changes in developmentthe role of nutrition and individual susceptibilitythe utility of bioinformaticsglobal and targeted gene expression changes
Information
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Out of stock
- Format:Hardback
- Pages:408 pages, 22 Tables, black and white; 17 Halftones, black and white; 22 Illustrations, color; 45 Il
- Publisher:Taylor & Francis Inc
- Publication Date:22/10/2008
- Category:
- ISBN:9781420054378
Other Formats
- Paperback / softback from £56.99
- PDF from £46.16
Information
-
Out of stock
- Format:Hardback
- Pages:408 pages, 22 Tables, black and white; 17 Halftones, black and white; 22 Illustrations, color; 45 Il
- Publisher:Taylor & Francis Inc
- Publication Date:22/10/2008
- Category:
- ISBN:9781420054378
