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Neurobiology of Huntington’s Disease : Applications to Drug Discovery, PDF eBook

Neurobiology of Huntington’s Disease : Applications to Drug Discovery PDF

Edited by Donald C. (Duke University Medical Center, Durham, North Carolina, USA) Lo, Robert E. (Buck Institute for Age Research, Novato, California, USA) Hughes

Part of the Frontiers in Neuroscience series

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In 1993, the genetic mutation responsible for Huntington's disease (HD) was identified.

Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse range of biochemical and genetic perturbations that see

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