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Ribosome-inactivating Proteins : Ricin and Related Proteins, PDF eBook

Ribosome-inactivating Proteins : Ricin and Related Proteins PDF

Edited by Fiorenzo Stirpe, Douglas Lappi

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This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs).

Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity.

The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain.

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