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Molecular Aspects of G Protein-Coupled Receptors : Interacting Proteins & Function, Hardback Book

Molecular Aspects of G Protein-Coupled Receptors : Interacting Proteins & Function Hardback

Edited by Franciso Ciruela, Rafael Lujan

Hardback

Description

In the recent years studies based on two-hybrid screens, proteomic, biochemical and cell biology approaches, have shown that intracellular domains of G protein-coupled receptors (GPCR) or heptaspanning membrane receptors (HSMRs) interact with intracellular proteins.

These interactions are the basis of a protein network associated to these receptors which includes scaffolding proteins containing one or several PDZ (post-synaptic density-95, discs large, zona occludens-1) domains, signalling proteins and proteins of the cytoskeleton.

The present book is focused on the emerging evidence for interactions of G protein-coupled receptors with scaffolding, cytoskeletal and signalling proteins that will play a role in the targeting, anchoring and functioning of these receptors in the plasma membrane, thus contributing to cell development and plasticity.

Information

  • Format:Hardback
  • Pages:309 pages, Illustrations, unspecified
  • Publisher:Nova Science Publishers Inc
  • Publication Date:
  • Category:
  • ISBN:9781600219153
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Information

  • Format:Hardback
  • Pages:309 pages, Illustrations, unspecified
  • Publisher:Nova Science Publishers Inc
  • Publication Date:
  • Category:
  • ISBN:9781600219153