Organocatalytic Dynamic Kinetic Resolution Hardback
by Helene (CNRS, France) Pellissier
Part of the Catalysis Series series
Hardback
Description
In a classical kinetic resolution, two enantiomers of a racemate are transformed into chiral products at different rates with a maximum theoretical yield of 50%.
However, the need to reduce costs and waste in synthesis have led to efforts to develop novel resolution procedures proceeding beyond this 50% limited yield.
This has led to the evolution of classical kinetic resolution into dynamic kinetic resolution (DKR), allowing a quantitative yield of one of the enantiomers.
DKR combines the resolution step of kinetic resolution with an in-situ racemization of the chirally-labile substrate.
It is only in the last two decades that chiral green organocatalysts have been demonstrated to be capable of promoting DKRs considerably expanding the synthetic scope of the powerful concept of DKR. Collecting all the developments in the field of DKR, this book shows that a wide variety of organocatalysts allow excellent levels of stereocontrol and yields in many types of transformations.
It is a great resource for academics and industrialists interested in green enantioselective catalytic reactions.
Information
-
Out of Stock - We are unable to provide an estimated availability date for this product
- Format:Hardback
- Pages:170 pages
- Publisher:Royal Society of Chemistry
- Publication Date:06/05/2022
- Category:
- ISBN:9781839165658
Information
-
Out of Stock - We are unable to provide an estimated availability date for this product
- Format:Hardback
- Pages:170 pages
- Publisher:Royal Society of Chemistry
- Publication Date:06/05/2022
- Category:
- ISBN:9781839165658
