Adverse Effects of Vaccines : Evidence and Causality Hardback
by Institute of Medicine, Board on Population Health and Public Health Practice, Committee to Review Adverse Effects of Vaccines
Edited by Ellen Wright Clayton, Erin Rusch, Andrew Ford, Kathleen Stratton
Hardback
Description
In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases.
Today, vaccines exist for many viral and bacterial diseases.
The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens.
The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers.
A key component of the legislation required the U.S.
Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others.
For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence.
It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines.
In addition, the evidence shows that vaccines do not cause several conditions.
For example, the MMR vaccine is not associated with autism or childhood diabetes.
Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors. Table of ContentsFront MatterSummary1 Introduction2 Approach3 Evaluating Biological Mechanisms of Adverse Events4 Measles, Mumps, and Rubella Vaccine5 Varicella Virus Vaccine6 Influenza Vaccine7 Hepatitis A Vaccine8 Hepatitis B Vaccine9 Human Papillomavirus Vaccine10 Diphtheria Toxoid, Tetanus Toxoid, and AcellularPertussisContaining Vaccines11 Meningococcal Vaccine12 Injection-Related Adverse Events13 Concluding CommentsAppendix A: GlossaryAppendix B: List of Adverse EventsAppendix C: Literature Search StrategyAppendix D: Causality Conclusion TablesAppendix E: ReferencesAppendix F: Committee BiosketchesAppendix G: Meeting AgendasIndex
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Out of Stock - We are unable to provide an estimated availability date for this product
- Format:Hardback
- Pages:894 pages
- Publisher:National Academies Press
- Publication Date:26/04/2012
- Category:
- ISBN:9780309214353
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Information
-
Out of Stock - We are unable to provide an estimated availability date for this product
- Format:Hardback
- Pages:894 pages
- Publisher:National Academies Press
- Publication Date:26/04/2012
- Category:
- ISBN:9780309214353
