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Interleukin-10, PDF eBook

Interleukin-10 PDF

Edited by Jan E.de Vries, Rene de Waal Malefyt

Part of the Molecular Biology Intelligence Unit series

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Description

The presented information reflects a state-of-the-art summary of the pleiotropic effects of IL-10 in vitro and in vivo and will contribute to our understanding of the role of ILj-10 in the immune system and its potential clinicial utility in the near future.

The book contains chapters in which the in vitro biological effects of IL-10 on both mouse and human lymphoid and myeloid cells are reviewed.

In addition, the role of IL-10 in transplantation, parasite infections, inflammation, infectious diseases and bone formation is described.

The effects of IL-10 in vivo are presented, describing an IL-10 transgenic mouse model, the IL-10 "knock-out" mouse, and the capacity of IL-10 to prevent lethal toxic shock in mice.

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