Fc Mediated Activity of Antibodies : Structural and Functional Diversity Paperback / softback
Edited by Jeffrey V. Ravetch, Falk Nimmerjahn
Part of the Current Topics in Microbiology and Immunology series
Paperback / softback
Description
This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination.
Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity.
The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved.
In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection.
In closing, it presents strategies for developing novel antibody-based vaccination approaches.
The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.
Information
-
Available to Order - This title is available to order, with delivery expected within 2 weeks
- Format:Paperback / softback
- Pages:150 pages, 12 Illustrations, color; 2 Illustrations, black and white; VII, 150 p. 14 illus., 12 illu
- Publisher:Springer Nature Switzerland AG
- Publication Date:19/09/2020
- Category:
- ISBN:9783030310554
Information
-
Available to Order - This title is available to order, with delivery expected within 2 weeks
- Format:Paperback / softback
- Pages:150 pages, 12 Illustrations, color; 2 Illustrations, black and white; VII, 150 p. 14 illus., 12 illu
- Publisher:Springer Nature Switzerland AG
- Publication Date:19/09/2020
- Category:
- ISBN:9783030310554
