Drug Metabolism and Transport : Molecular Methods and Mechanisms Hardback
Edited by Lawrence H. Lash
Part of the Methods in Pharmacology and Toxicology series
Hardback
Description
A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals.
The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases.
Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy.
Information
-
Item not Available
- Format:Hardback
- Pages:388 pages, 110 Illustrations, black and white; X, 388 p. 110 illus.
- Publisher:Humana Press Inc.
- Publication Date:24/09/2004
- Category:
- ISBN:9781588293244
Information
-
Item not Available
- Format:Hardback
- Pages:388 pages, 110 Illustrations, black and white; X, 388 p. 110 illus.
- Publisher:Humana Press Inc.
- Publication Date:24/09/2004
- Category:
- ISBN:9781588293244
