Untranslated Gene Regions and Other Non-coding Elements : Regulation of Eukaryotic Gene Expression Paperback / softback
by Lucy W. Barrett, Sue Fletcher, Steve D. Wilton
Part of the SpringerBriefs in Biochemistry and Molecular Biology series
Paperback / softback
Description
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes.
Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression.
The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns.
In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation.
This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.?
Information
-
Out of stock
- Format:Paperback / softback
- Pages:56 pages, 2 Illustrations, color; VIII, 56 p. 2 illus. in color.
- Publisher:Springer Basel
- Publication Date:09/07/2013
- Category:
- ISBN:9783034806787
Other Formats
- PDF from £38.24
Information
-
Out of stock
- Format:Paperback / softback
- Pages:56 pages, 2 Illustrations, color; VIII, 56 p. 2 illus. in color.
- Publisher:Springer Basel
- Publication Date:09/07/2013
- Category:
- ISBN:9783034806787
