Preclinical Drug Development Hardback
Edited by Mark Rogge, David R. Taft
Part of the Drugs and the Pharmaceutical Sciences series
Hardback
Description
Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development.
Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials.
Highlights of the Second Edition include: PharmacokineticsModeling and simulationFormulation and routes of administrationToxicity evaluationsThe assessment of drug absorption and metabolismInterspecies scaling Lead molecule selection and optimization via profilingScreening using in silico and in vitro toxicity evaluations The book also includes case studies on preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development, a review of ICH preclinical guidelines, and experimental methods used to study membrane drug transport and metabolism.
This guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences.
Information
-
Only a few left - usually despatched within 24 hours
- Format:Hardback
- Pages:380 pages, 16 Illustrations, color; 58 Illustrations, black and white
- Publisher:Taylor & Francis Inc
- Publication Date:25/09/2009
- Category:
- ISBN:9781420084726
Information
-
Only a few left - usually despatched within 24 hours
- Format:Hardback
- Pages:380 pages, 16 Illustrations, color; 58 Illustrations, black and white
- Publisher:Taylor & Francis Inc
- Publication Date:25/09/2009
- Category:
- ISBN:9781420084726
