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Drug Metabolism and Pharmacokinetics, Hardback Book

Drug Metabolism and Pharmacokinetics Hardback

Edited by Mithun Rudrapal

Part of the Pharmaceutical Science series

Hardback

Out of stock

Description

This book, and #60;i and #62;Drug Metabolism and Pharmacokinetics and #60;/i and #62;, delivers the latest information on biotransformation and other pharmacokinetic parameters required to assess drug safety in drug discovery and development.

Drug metabolism and pharmacokinetics (DMPK) is considered a rational strategy for the design, optimization, and selection of successful drug candidates in the pre-clinical stages of drug discovery.

The evaluation of various pharmacokinetic parameters such as aqueous solubility, lipophilicity, cell permeability, bioavailability, protein binding, andmetabolism and elimination half-life, drug–drug interactions (DDIs), and toxicokinetics is essential for a candidate drug to become a successful therapeutic agent.

This book discusses recent advances in in-silico tools and in vitro/in vivo experimental techniques applied inpharmacokinetic, metabolomic, and bioanalytical studies. and #60;br and #62;Key Features: and #60;br and #62;• Presents pharmacokinetic and biotransformation parameters used for pre-clinical safetyevaluations and #60;br and #62;• Depicts experimental and biophysical techniques used in bioanalytical and metabolomicstudies and #60;br and #62;• Summarizes in silico, in vitro, and in vivo methods used in drug–enzyme interactions, drug–drug interactions, and toxicokinetics and #60;br and #62;Written by a global team of experts, this book is a valuable resource for drug discovery scientists,drug developers, medicinal chemists, pharmacologists, biochemists, clinicians, biomedicalscientists, healthcare professionals, researchers, teaching faculty, and students.

Information

  • Out of stock

  • Format:Hardback
  • Pages:134 pages
  • Publisher:IntechOpen
  • Publication Date:
  • Category:
  • ISBN:9780850141474

£119.00

Out of stock
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Information

  • Out of stock

  • Format:Hardback
  • Pages:134 pages
  • Publisher:IntechOpen
  • Publication Date:
  • Category:
  • ISBN:9780850141474