Multiple Testing Procedures with Applications to Genomics Paperback / softback
by Sandrine Dudoit, Mark J. van der Laan
Part of the Springer Series in Statistics series
Paperback / softback
Description
This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS.
These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms.
The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and test statistics.
Information
-
Item not Available
- Format:Paperback / softback
- Pages:590 pages, XXXIII, 590 p.
- Publisher:Springer-Verlag New York Inc.
- Publication Date:12/02/2010
- Category:
- ISBN:9781441923790
Other Formats
- Hardback from £154.85
- PDF from £118.58
Information
-
Item not Available
- Format:Paperback / softback
- Pages:590 pages, XXXIII, 590 p.
- Publisher:Springer-Verlag New York Inc.
- Publication Date:12/02/2010
- Category:
- ISBN:9781441923790