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Phosphodiesterases and Their Inhibitors, Hardback Book

Phosphodiesterases and Their Inhibitors Hardback

Edited by Spiros (Pfizer, Groton, USA) Liras, Andrew S. (Imperial College, London, UK) Bell

Part of the Methods & Principles in Medicinal Chemistry series

Hardback

Description

Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors.

Drug development options for all major human PDE families are discussed and cover diverse therapeutic fields, such as neurological/psychiatric, cardiovascular/metabolic, pain, and allergy/respiratory diseases.

Finally, emerging chemotherapeutic applications of PDE inhibitors against malaria and other tropical diseases are discussed.

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