The Neuromodulators : Volume 64 Hardback
Edited by Ronald J. (Louisiana State University Medical Center, School of Medicine, Baton Rouge, U.S. Bradley, R. Adron (University of Texas, USA) Harris, Peter (Division of Pharmacology and Therapeutics, GKT School of Biomedical Sciences, King's Jenner
Part of the International Review of Neurobiology series
Hardback
Description
Glutamate and GABA are the main information carrying neurotransmitters in the brain.
Their action is modulated by a further series of small molecules called neuromodulators.
The major neuromodulators in the brain are acetylcholine (both muscarinic and nicotinic), dopamine, norepinephrine, epinephrine and serotonin. These have an enormous range of functions in a wide variety of brain mechanisms.
This book attempts to give a general overview of this field with a section devoted to each of these.
Each section starts with anatomy, both structural and functional.
The various types of receptors for these agents are described and then the effects of stimulating these receptors.
These receptors trigger a variety of electrical reactions that generally involve potassium, sodium or calcium channels. Also reviewed are other receptors that trigger a wide variety of post-synaptic signaling cascades that influence a large number of neuronal functions including receptor sensitivity, synaptic plasticity and gene manipulation.
Finally the relevance of these systems to disease states is detailed.
There are many reviews of individual neuromodulators but this is the only book where one author attempts to cover the whole field.
Information
-
Out of stock
- Format:Hardback
- Pages:296 pages
- Publisher:Elsevier Science Publishing Co Inc
- Publication Date:28/07/2005
- Category:
- ISBN:9780123668653
Information
-
Out of stock
- Format:Hardback
- Pages:296 pages
- Publisher:Elsevier Science Publishing Co Inc
- Publication Date:28/07/2005
- Category:
- ISBN:9780123668653
