Pharmacokinetics and Metabolism in Drug Design Hardback
Edited by Dennis A. (Pfizer Global Research & Development) Smith, Charlotte (Pfizer Global R&D, Sandwich, UK) Allerton, Amit S. (Pfizer Global R&D, Groton, USA) Kalgutkar, Han van de (formerly AstraZeneca, Cheshire, UK) Waterbeemd, Don K. (Pfizer Global Research & Development) Walker
Part of the Methods & Principles in Medicinal Chemistry series
Hardback
Description
In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties.
Although the previous chapter layout has been retained, substantial revisions have been made, with new topics such as pro-drugs, active metabolites and transporters covered in detail in a manner useful to the Drug Discovery scientist.
The authors discuss the parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. While aimed at all those dealing professionally with the development and application of pharmaceutical substances, the readily comprehensible style makes this book equally suitable for students of pharmacy and related subjects.
Uniquely comprehensive, the book relates physicochemistry and chemical structure to pharmacokinetic properties and ultimately drug efficacy and safety.
Information
-
Only a few left - usually despatched within 24 hours
- Format:Hardback
- Pages:268 pages
- Publisher:Wiley-VCH Verlag GmbH
- Publication Date:04/04/2012
- Category:
- ISBN:9783527329540
£116.95
£104.15
Information
-
Only a few left - usually despatched within 24 hours
- Format:Hardback
- Pages:268 pages
- Publisher:Wiley-VCH Verlag GmbH
- Publication Date:04/04/2012
- Category:
- ISBN:9783527329540
