Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of -Aryl Ketones Hardback
by Robert Doran
Part of the Springer Theses series
Hardback
Description
This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis.
Firstly, a new methodology, developed by our research group, which allows the asymmetric synthesis of lactones, a structural unit ubiquitous in natural products, was utilised in the synthesis of a number of natural product analogues that showed significant biological activity.
Secondly, the development of a catalytic asymmetric synthesis of a key structural motif present in a number of natural products and pharmaceuticals was accomplished.
During the course of this work we discovered dual stereo control, which is significant because it allows the configuration of a new stereo centre to be controlled by a simple change of proton source.
Information
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Item not Available
- Format:Hardback
- Pages:202 pages, 3 Illustrations, color; 255 Illustrations, black and white; XXI, 202 p. 258 illus., 3 ill
- Publisher:Springer International Publishing AG
- Publication Date:25/06/2015
- Category:
- ISBN:9783319205434
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Information
-
Item not Available
- Format:Hardback
- Pages:202 pages, 3 Illustrations, color; 255 Illustrations, black and white; XXI, 202 p. 258 illus., 3 ill
- Publisher:Springer International Publishing AG
- Publication Date:25/06/2015
- Category:
- ISBN:9783319205434
