Please note: In order to keep Hive up to date and provide users with the best features, we are no longer able to fully support Internet Explorer. The site is still available to you, however some sections of the site may appear broken. We would encourage you to move to a more modern browser like Firefox, Edge or Chrome in order to experience the site fully.

Supporting your high street Find out how »
TDP-43 and Neurodegeneration : From Bench to Bedside, Paperback / softback Book

TDP-43 and Neurodegeneration : From Bench to Bedside Paperback / softback

Edited by Vijay (Assistant Professor, Amity Institute of Neuropsychology and Neurosciences, Amity Unive Kumar, Manoj Kumar (Department of Psychiatry, Icahn School of Medicine at Mount Sina, New York, NY Jaiswal

Paperback / softback

Out of stock

Description

Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features.

TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies.

The book summarizes TDP-43's structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics.

It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases.

This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders.

Information

£115.00

Out of stock
Add to Basket
Sign in to add to wishlist
 
Free Home Delivery

on all orders

 
Pick up orders

from local bookshops

Information